BDBM50207849 CHEMBL246151::N-(2-chloro-5-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)-3-isopropylbenzamide

SMILES CNc1cc(ccn1)-c1cccnc1Oc1ccc(Cl)c(NC(=O)c2cccc(c2)C(C)C)c1

InChI Key InChIKey=SBRDWSXZGGLNQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207849   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50207849(CHEMBL246151 | N-(2-chloro-5-(3-(2-(methylamino)py...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50207849(CHEMBL246151 | N-(2-chloro-5-(3-(2-(methylamino)py...)
Affinity DataIC50:  9nMAssay Description:Inhibition of KDR after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed