BDBM50209149 1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazole-5-carbonyl)-piperidine-3-carboxylic acid::CHEMBL245734

SMILES OC(=O)C1CCCN(C1)C(=O)c1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1

InChI Key InChIKey=WBRHCOIAJKWTPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209149   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209149(1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...)
Affinity DataIC50:  4.84E+3nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209149(1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of Flt1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209149(1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed