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BDBM50209201 CHEMBL233848::N-(5-chloro-3-(4-(2-chloro-5-(trifluoromethyl)phenyl)-5-cyano-6-oxo-1,6-dihydropyridin-2-yl)-2-hydroxybenzyl)-1-acetylpiperidine-4-carboxamide

InChI string: InChI=1S/C28H23Cl2F3N4O4/c1-14(38)37-6-4-15(5-7-37)26(40)35-13-16-8-18(29)10-21(25(16)39)24-11-19(22(12-34)27(41)36-24)20-9-17(28(31,32)33)2-3-23(20)30/h2-3,8-11,15,39H,4-7,13H2,1H3,(H,35,40)(H,36,41)

SMILES: CC(=O)N1CCC(CC1)C(=O)NCc1cc(Cl)cc(c1O)-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1

InChI Key: InChIKey=HDCCFRZARJMJEW-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209201   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209201
PNG
(CHEMBL233848 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Show SMILES CC(=O)N1CCC(CC1)C(=O)NCc1cc(Cl)cc(c1O)-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1
Show InChI InChI=1S/C28H23Cl2F3N4O4/c1-14(38)37-6-4-15(5-7-37)26(40)35-13-16-8-18(29)10-21(25(16)39)24-11-19(22(12-34)27(41)36-24)20-9-17(28(31,32)33)2-3-23(20)30/h2-3,8-11,15,39H,4-7,13H2,1H3,(H,35,40)(H,36,41)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 48n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair