BDBM50210296 3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)indeno[1,2-c]pyrazol-4(1H)-one::CHEMBL387971
SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc2-c3ccc(CN4CCN(C)CC4)cc3C(=O)c12
InChI Key InChIKey=YACXOXQTGJXYNX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50210296
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of hERG expressed in HEK293 cells assessed as effect on ionic current by patch clamp assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair