BDBM50212684 2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydro-isoindol-1-ylideneamine::CHEMBL247323

SMILES COc1ccccc1CN1Cc2cc(OC(F)(F)F)ccc2C1=N

InChI Key InChIKey=JWWCPLDJCABVCP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212684   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212684(2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydr...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212684(2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydr...)
Affinity DataIC50:  5.90nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed