BDBM50212772 CHEMBL232381::N-allyl-1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyclohexyl-1H-benzo[d]imidazole-5-carboxamide

SMILES NC(=O)CCn1c(NC(=O)c2ccc(Br)cc2)nc2cc(ccc12)C(=O)N(CC=C)C1CCCCC1

InChI Key InChIKey=GFSUPLWNXMKMDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212772   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(CHEMBL232381 | N-allyl-1-(3-amino-3-oxopropyl)-2-(...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(CHEMBL232381 | N-allyl-1-(3-amino-3-oxopropyl)-2-(...)
Affinity DataIC50:  1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed