BDBM50212794 1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobenzamido)-N-methyl-1H-benzo[d]imidazole-5-carboxamide::CHEMBL234392

SMILES CN(C1CCCCC1)C(=O)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(F)cc3)nc2c1

InChI Key InChIKey=IYYJMJYGTSRZFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212794   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50:  4.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed