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BDBM50212993 CHEMBL305928

SMILES: C1CN=C(NC2CCCCCC2)O1

InChI Key: InChIKey=DAIRUBYTBODIKT-UHFFFAOYSA-N

Data: 6 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50212993   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
5.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-2A adrenergic receptor by the displacement of [3H]rauwolscine


Citation and Details
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens)
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
9.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-2B adrenergic receptor by the displacement of [3H]rauwolscine


Citation and Details
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
33n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-2C adrenergic receptor by the displacement of [3H]rauwolscine


Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
2.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-1C adrenergic receptor by the displacement of [3H]prazosin


Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
3.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-1A adrenergic receptor by the displacement of [3H]prazosin


Citation and Details
More data for this
Ligand-Target Pair
Adrenergic alpha1B


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
3.55E+13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards human Alpha-1B adrenergic receptor by the displacement of [3H]prazosin


Citation and Details
More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/an/an/a 38n/an/an/an/a


TBA

Assay Description
Agonistic activity towards human Alpha-2A adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...


Citation and Details
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens)
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/an/an/a 214n/an/an/an/a


TBA

Assay Description
Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...


Citation and Details
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50212993
PNG
(CHEMBL305928)
Show SMILES C1CN=C(NC2CCCCCC2)O1
Show InChI InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/an/an/a 78n/an/an/an/a


TBA

Assay Description
Agonistic activity towards human Alpha-2C adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...


Citation and Details
More data for this
Ligand-Target Pair