BDBM50213034 1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-propenone::1-(2,4-Dihydroxyphenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one::1-(2,4-dihydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one::2',4'-dihydroxy-4-methoxychalcone::CHEMBL182653

SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2O)cc1

InChI Key InChIKey=ADRQFDIWPRFKSP-RUDMXATFSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50213034   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)TBA
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  930nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50213034(1-(2,4-Dihydroxy-phenyl)-3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed