BDBM50213533 CHEMBL228607::N-((1r,4r)-4-(4-(2-(2,2-difluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide

SMILES COc1ccc(cc1OC)S(=O)(=O)N[C@H]1CC[C@@H](CC1)N1CCC(CC1)c1ccccc1OCC(F)F

InChI Key InChIKey=QLLKZBYEHJGRHK-MEMLXQNLSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50213533   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human cloned adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human cloned adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  86nMAssay Description:Binding affinity to human cloned adrenergic alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  86nMAssay Description:Binding affinity to human cloned adrenergic alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  88nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  88nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  681nMAssay Description:Binding affinity to human cloned adrenergic alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213533(CHEMBL228607 | N-((1r,4r)-4-(4-(2-(2,2-difluoroeth...)
Affinity DataKi:  681nMAssay Description:Binding affinity to human cloned adrenergic alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed