BDBM50214097 4-(3-(4-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)isoquinoline::CHEMBL400858

SMILES Cc1cccc2[nH]c(nc12)-c1[nH]nc2ncc(cc12)-c1cncc2ccccc12

InChI Key InChIKey=KYLXOJOIXAIVQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214097   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214097(4-(3-(4-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazo...)
Affinity DataIC50:  97nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214097(4-(3-(4-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214097(4-(3-(4-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazo...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed