BDBM50215405 (1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-5-phosphonooxymethyl-bicyclo[3.1.0]hex-2-yl)-9H-purine-2-carboxylic acid::CHEMBL226857

SMILES CNc1nc(nc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@]2(COP(O)(O)=O)C[C@H]12)C(O)=O

InChI Key InChIKey=GUOMGUSMLUKJOQ-WUUFAPOGSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215405   

TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataKi:  1.43E+3nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataIC50:  871nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataIC50:  870nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed