BDBM50215430 2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxopyrazin-1(2H)-yl)-N-((2-aminopyrimidin-4-yl)methyl)acetamide::CHEMBL388439

SMILES Nc1cccc(c1)-c1c(Cl)nc(NC2CCC2)c(=O)n1CC(=O)NCc1ccnc(N)n1

InChI Key InChIKey=JLWGOTTZQKBHMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215430   

TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215430(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215430(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215430(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed