BDBM50215680 CHEMBL250953::sodium (3R,5R)-7-[3-(4-fluoro-phenyl)-1-isopropyl-4-phenyl-5-(4-sulfamoyl-phenylcarbamoyl)-1H-pyrrol-2-yl]-3,5-dihydroxy-heptanoate

SMILES CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=ZBCQTJGKEZGMGJ-CLJLJLNGSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215680   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215680(CHEMBL250953 | sodium (3R,5R)-7-[3-(4-fluoro-pheny...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed