BDBM50215781 2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide::CHEMBL391781

SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccncc3)cc2OC1(F)F

InChI Key InChIKey=DKDIYRYSJHNWTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215781   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215781(2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215781(2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed