BDBM50216002 CHEMBL247347::cis-4-((2-methylquinolin-4-yl)methoxy)-N-(3-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-tetrahydro-2H-pyran-4-yl)benzamide

SMILES Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2c2n[nH]c(=S)[nH]2)c2ccccc2n1

InChI Key InChIKey=XZCDAPHMYWQDPY-RBBKRZOGSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50216002   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataKi: >4.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataKi: >6.02E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataKi: >6.37E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50216002(CHEMBL247347 | cis-4-((2-methylquinolin-4-yl)metho...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed