BDBM50219326 PYRAZOLOPYRIMIDINE 1

SMILES CN(C)CCNC(=O)c1ccc(\C=N\Nc2ncnc3n(ncc23)-c2cccc3[nH]cnc23)cc1

InChI Key InChIKey=QNUBZASKWDMCAQ-PNQUVVCRSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219326   

TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219326(PYRAZOLOPYRIMIDINE 1)
Affinity DataEC50:  2.33E+3nMAssay Description:Inhibition of glycogen synthesis in rat skeletal muscle L6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50219326(PYRAZOLOPYRIMIDINE 1)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation countingMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219326(PYRAZOLOPYRIMIDINE 1)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of glycogen synthase kinase-3 (GSK3-beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed