BDBM50220015 (5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]phenyl}-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one::CHEMBL398160

SMILES OCc1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O

InChI Key InChIKey=WOCKQPIYHQRKEQ-HNNXBMFYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220015   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human liver MAOA expressed in yeastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220015((5R)-3-{3-fluoro-4-[6-(hydroxymethyl)pyridin-3-yl]...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed