BDBM50220185 1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea::CHEMBL243668::N-[3-fluoro-4'-(trifluoromethyl)-4-biphenylyl]urea

SMILES NC(=O)Nc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IJERYHSCLRZINL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220185   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50220185(1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...)
Affinity DataIC50:  100nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50220185(1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed