BDBM50220573 1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-yl)-4-(4-fluorophenyl)piperidin-4-ol::CHEMBL401406

SMILES CC(C(O)c1ccc(O)c(Cl)c1)N1CCC(O)(CC1)c1ccc(F)cc1

InChI Key InChIKey=NXKIHQUDEGCERT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220573   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220573(1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220573(1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed