BDBM50222913 4'-{5-[4-(isopropylamino-methyl)-phenylamino]-2H-pyrazol-3-yl}-biphenyl-2,4-diol::CHEMBL398606
SMILES CC(C)NCc1ccc(Nc2cc(n[nH]2)-c2ccc(cc2)-c2ccc(O)cc2O)cc1
InChI Key InChIKey=MYHOUKHXSVKHBA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50222913
Affinity DataKi: 0.360nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CDK1 expressed in Sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of PIM2More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ABLMore data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of MASKMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human SGKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human LCKMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of CAMK1More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Activity at human CHK1 in CA46 cells by histone H3 ELISA assayMore data for this Ligand-Target Pair