BDBM50223475 6-(3-aminopropyl)-4-(2,4-dichlorophenyl)-9-(1H-pyrazol-4-yl)benzo[h]isoquinolin-1(2H)-one::CHEMBL250459

SMILES NCCCc1cc2c(c[nH]c(=O)c2c2cc(ccc12)-c1cn[nH]c1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=XKEASKIOEKUJCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223475   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223475(6-(3-aminopropyl)-4-(2,4-dichlorophenyl)-9-(1H-pyr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human Chk1 expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed