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BDBM50224105 1,5-bis-(4-methylphenyl)-3-trifluoromethyl-pyrazole::1,5-dip-tolyl-3-(trifluoromethyl)-1H-pyrazole::CHEMBL244130

SMILES: Cc1ccc(cc1)-c1cc(nn1-c1ccc(C)cc1)C(F)(F)F

InChI Key: InChIKey=IUCYMYXIAQVGFQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224105   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2C9


(Homo sapiens (human))
BDBM50224105
PNG
(1,5-bis-(4-methylphenyl)-3-trifluoromethyl-pyrazol...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C18H15F3N2/c1-12-3-7-14(8-4-12)16-11-17(18(19,20)21)22-23(16)15-9-5-13(2)6-10-15/h3-11H,1-2H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



AstraZeneca R&D Mölndal

Curated by ChEMBL


Assay Description
Inhibition of recombinant CYP2C9 by fluorescence inhibition assay


J Med Chem 50: 5382-91 (2007)


Article DOI: 10.1021/jm070745g
BindingDB Entry DOI: 10.7270/Q2TB16MF
More data for this
Ligand-Target Pair