BDBM50224413 CHEMBL392634::N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-morpholin-4-ylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
SMILES Fc1cccc([C@@H]2CC[C@@H](NC(=O)N3CCC(CC3)n3c4cccnc4[nH]c3=O)C(=O)N(CCN3CCOCC3)C2)c1F
InChI Key InChIKey=KCVQZSVWXQUJHF-HYBUGGRVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50224413
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP production in presence of 50% human serumMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair