BDBM50224453 (1S,5S)-3-(5-chloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]-heptane::CHEMBL238666

SMILES Clc1cncc(c1)N1C[C@@H]2CN[C@@H]2C1

InChI Key InChIKey=OYRMPONTNDKOTG-OIBJUYFYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224453   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Neuroscience Research

Curated by ChEMBL

LigandBDBM50224453((1S,5S)-3-(5-chloropyridin-3-yl)-3,6-diazabicyclo[...)Copy SMILESCopy InChI

Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at recombinant human alpha-4-beta-2 nAChR expressed in HEK293 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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