BDBM50224770 (2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol::CHEMBL251997

SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NC3CCCC3)nc(Cl)nc12

InChI Key InChIKey=MMPAUXMIDJWGFO-ROMFRFKVSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50224770   

TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  1.80nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptors of bovine cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  3.37nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  3.90nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  1.15E+3nMAssay Description:Agonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as activation of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  4.56E+3nMAssay Description:Displacement of [3H]CGS21680 from adenosine A1 receptor in bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  9.58E+3nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [3H]CGS21680 from adenosine A1 receptor in pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224770((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...)
Affinity DataKi:  3.76E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed