BDBM50226071 (S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl)benzyl)-3-aminopyrrolidine-4-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL399726

SMILES Cc1nnc(o1)-c1ccc(CN2C[C@H](N)[C@@H](C2)C(=O)N2CCC[C@H]2C#N)cc1

InChI Key InChIKey=VFSLWMDPHBMMRV-KSZLIROESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226071   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226071((S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  7.04E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226071((S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226071((S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed