BDBM50226457 6-(3-(pyridin-3-yl)phenethyl)-2-amino-3-methylpyrimidin-4(3H)-one::CHEMBL235753

SMILES Cn1c(N)nc(CCc2cccc(c2)-c2cccnc2)cc1=O

InChI Key InChIKey=JKPVKTCZXDPUPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226457   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226457(6-(3-(pyridin-3-yl)phenethyl)-2-amino-3-methylpyri...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of BACE1 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226457(6-(3-(pyridin-3-yl)phenethyl)-2-amino-3-methylpyri...)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of BACE1 by IGEN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed