BDBM50226458 2-amino-6-(3,4-dichlorophenyl)-6-methyl-5,6-dihydro-3H-pyrimidin-4-one::CHEMBL397162

SMILES CC1(CC(=O)NC(N)=N1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=BSPRSYCGMJBMNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226458   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226458(2-amino-6-(3,4-dichlorophenyl)-6-methyl-5,6-dihydr...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of BACE1 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226458(2-amino-6-(3,4-dichlorophenyl)-6-methyl-5,6-dihydr...)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed