BDBM50226804 CHEMBL88149

SMILES CCOC(=O)C1=C(C)N=C(NC1c1cccc(c1)[N+]([O-])=O)OC

InChI Key InChIKey=RVBQIBMRQBVLMH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226804   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50226804(CHEMBL88149)
Affinity DataIC50:  710nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50226804(CHEMBL88149)
Affinity DataKd:  105nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed