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BDBM50227248 CHEMBL1237321

SMILES: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.Fc1ccc(cc1)C1CC(N2CCN(CCN3CCN=C3S)CC2)c2ccccc12

InChI Key: InChIKey=HANJJACYKOGAHN-SPIKMXEPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227248   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227248
PNG
(CHEMBL1237321)
Show SMILES OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.Fc1ccc(cc1)C1CC(N2CCN(CCN3CCN=C3S)CC2)c2ccccc12
Show InChI InChI=1S/C24H29FN4S.2C4H4O4/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30;2*5-3(6)1-2-4(7)8/h1-8,22-23H,9-17H2,(H,26,30);2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair