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BDBM50227641 CHEMBL297014

SMILES: CCn1cc(Cc2ccc(cc2OC)C(O)=O)c2cc(NC(=O)CC3CCCC3)ccc12

InChI Key: InChIKey=FBWUGXPSCDEGEI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227641   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50227641
PNG
(CHEMBL297014)
Show SMILES CCn1cc(Cc2ccc(cc2OC)C(O)=O)c2cc(NC(=O)CC3CCCC3)ccc12
Show InChI InChI=1S/C26H30N2O4/c1-3-28-16-20(13-18-8-9-19(26(30)31)14-24(18)32-2)22-15-21(10-11-23(22)28)27-25(29)12-17-6-4-5-7-17/h8-11,14-17H,3-7,12-13H2,1-2H3,(H,27,29)(H,30,31)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
71n/an/an/an/an/an/an/an/a



ICI Pharmaceuticals Group

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]LTD4 on guinea pig lung parenchymal membranes.


J Med Chem 33: 1781-90 (1990)


Article DOI: 10.1021/jm00168a037
BindingDB Entry DOI: 10.7270/Q2862FDP
More data for this
Ligand-Target Pair