BDBM50227722 CHEMBL398641::N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-biphenyl-4-yl]-piperidine-1-sulfonyl}-2-methyl-propionamide

SMILES Cc1cc(ccc1-c1cccc(OCCO)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO

InChI Key InChIKey=XMVZJCLXRBLZHB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50227722   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  406nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  262nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...)
Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed