BDBM50228646 5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline-2,4(1H,3H)-dione::CHEMBL253708

SMILES CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(O)cc1

InChI Key InChIKey=LDQVCKQENSZRBU-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50228646   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi:  12.3nMAssay Description:Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from human cloned dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-LSD from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50228646(5,7-dichloro-3-(4-hydroxyphenyl)-3-methylquinoline...)
Affinity DataIC50:  615nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of 5-HT-stimulated cAMP accumulation after 20 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed