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BDBM50228826 CHEMBL317379

SMILES: COc1ccc(cc1OC1C2CC3CC(C2)CC1C3)C1CNC(=O)N1C

InChI Key: InChIKey=JUPMFMQSGHTGKC-UHFFFAOYNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228826   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228826
PNG
(CHEMBL317379)
Show SMILES COc1ccc(cc1OC1C2CC3CC(C2)CC1C3)C1CNC(=O)N1C
Show InChI InChI=1/C21H28N2O3/c1-23-17(11-22-21(23)24)14-3-4-18(25-2)19(10-14)26-20-15-6-12-5-13(8-15)9-16(20)7-12/h3-4,10,12-13,15-17,20H,5-9,11H2,1-2H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of calcium-independent Phosphodiesterase 4


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228826
PNG
(CHEMBL317379)
Show SMILES COc1ccc(cc1OC1C2CC3CC(C2)CC1C3)C1CNC(=O)N1C
Show InChI InChI=1/C21H28N2O3/c1-23-17(11-22-21(23)24)14-3-4-18(25-2)19(10-14)26-20-15-6-12-5-13(8-15)9-16(20)7-12/h3-4,10,12-13,15-17,20H,5-9,11H2,1-2H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- rolipram binding to rat cerebral cortex membranes


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair