BDBM50229083 2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-2-methylbenzoyl)piperazin-1-yl)ethanone::CHEMBL254895

SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC1)C(=O)CN

InChI Key InChIKey=KVPNOQAXVUMKFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229083   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229083(2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...)
Affinity DataIC50:  540nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229083(2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229083(2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...)
Affinity DataIC50:  430nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50229083(2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed