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BDBM50229421 CHEMBL418901

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(O)=O

InChI Key: InChIKey=DVPVJSBHCCXIQP-WIGBTLJFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50229421
PNG
(CHEMBL418901)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(O)=O
Show InChI InChI=1S/C30H42N6O7/c1-5-19(4)25(29(40)41)34-26(37)23-12-9-13-36(23)28(39)22(14-21-15-31-17-32-21)33-27(38)24(18(2)3)35-30(42)43-16-20-10-7-6-8-11-20/h6-8,10-11,15,17-19,22-25H,5,9,12-14,16H2,1-4H3,(H,31,32)(H,33,38)(H,34,37)(H,35,42)(H,40,41)/t19-,22-,23-,24-,25-/m0/s1
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Similars

Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity as antagonist of AII on guinea pig ileum


J Med Chem 34: 2402-10 (1991)


Article DOI: 10.1021/jm00112a014
BindingDB Entry DOI: 10.7270/Q2VD71PJ
More data for this
Ligand-Target Pair