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BDBM50229957 CHEMBL153459

SMILES: [H][C@@]12CC=CCC1(CCN(CC1CC1)C2)c1cccc(O)c1

InChI Key: InChIKey=MNMYIWJGEBJRKS-KKFHFHRHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229957   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu/kappa/delta


(Homo sapiens (Human))
BDBM50229957
PNG
(CHEMBL153459)
Show SMILES Oc1cccc(c1)C12CCN(CC3CC3)C[C@@H]1CC=CC2
Show InChI InChI=1S/C19H25NO/c21-18-6-3-5-16(12-18)19-9-2-1-4-17(19)14-20(11-10-19)13-15-7-8-15/h1-3,5-6,12,15,17,21H,4,7-11,13-14H2/t17-,19?/m0/s1
PDB

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DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against opioid receptor in Guinea pig ileum


J Med Chem 35: 48-56 (1992)


Article DOI: 10.1021/jm00079a005
BindingDB Entry DOI: 10.7270/Q2J105DC
More data for this
Ligand-Target Pair