BDBM50230174 CHEMBL4085495

SMILES Nc1n[nH]c2cccc(-c3cccc(NC(=O)C4(CC4)C(=O)Nc4cc(Br)cc(c4)C(F)(F)F)c3)c12

InChI Key InChIKey=FOEQINTXCQEBGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230174   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230174(CHEMBL4085495)
Affinity DataIC50:  613nMAssay Description:Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230174(CHEMBL4085495)
Affinity DataIC50:  2nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50230174(CHEMBL4085495)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed