BDBM50230353 CHEMBL4075188
SMILES Ic1ccc(cc1)C(=O)C(=S)N1CCOCC1
InChI Key InChIKey=MGBANFQMLFPFNN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50230353
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair