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BDBM50230390 CHEBI:48556::MEDETOMIDINE HYDROCHLORIDE::MPV-785::Medetomidine HCl

SMILES: Cl.CC(c1c[nH]cn1)c1cccc(C)c1C

InChI Key: InChIKey=VPNGEIHDPSLNMU-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230390   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50230390
PNG
(CHEBI:48556 | MEDETOMIDINE HYDROCHLORIDE | MPV-785...)
Show SMILES Cl.CC(c1c[nH]cn1)c1cccc(C)c1C
Show InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



Ohio State University

Curated by ChEMBL


Assay Description
Compound was evaluated for Adrenergic activity in Alpha-2 adrenergic receptor of human platelets


J Med Chem 35: 750-5 (1992)


Article DOI: 10.1021/jm00082a017
BindingDB Entry DOI: 10.7270/Q27H1MTJ
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50230390
PNG
(CHEBI:48556 | MEDETOMIDINE HYDROCHLORIDE | MPV-785...)
Show SMILES Cl.CC(c1c[nH]cn1)c1cccc(C)c1C
Show InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 310n/an/an/an/a



Ohio State University

Curated by ChEMBL


Assay Description
Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta


J Med Chem 35: 750-5 (1992)


Article DOI: 10.1021/jm00082a017
BindingDB Entry DOI: 10.7270/Q27H1MTJ
More data for this
Ligand-Target Pair