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BDBM50230423 CHEMBL171875

SMILES: CCCCc1cc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=QRAHMDAQLMKHFS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230423   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230423
PNG
(CHEMBL171875)
Show SMILES CCCCc1cc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C26H25NO2/c1-2-3-9-22-17-21-8-4-7-12-25(21)27(22)18-19-13-15-20(16-14-19)23-10-5-6-11-24(23)26(28)29/h4-8,10-17H,2-3,9,18H2,1H3,(H,28,29)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair