BDBM50230567 CHEMBL4070053

SMILES NP(=O)(OCCCC(=O)Oc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)N(CCCl)CCCl

InChI Key InChIKey=KKNXUMNCAJWDKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230567   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50230567(CHEMBL4070053)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50230567(CHEMBL4070053)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed