BindingDB logo
myBDB logout

BDBM50230690 CHEMBL3143997

SMILES: NC1=NC(=O)C2NC=C([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=N1

InChI Key: InChIKey=DQFWBDNNOSWHRZ-SOJYJFKNNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230690   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (Human))
BDBM50230690
PNG
(CHEMBL3143997)
Show SMILES NC1=NC(=O)C2NC=C([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=N1
Show InChI InChI=1/C11H14N4O5/c12-11-14-5-3(1-13-6(5)10(19)15-11)9-8(18)7(17)4(2-16)20-9/h1,4,6-9,13,16-18H,2H2,(H2,12,15,19)/t4-,6?,7-,8-,9+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.90E+3n/an/an/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Ability to inhibit purine nucleoside phosphorylase (PNP)


J Med Chem 35: 1605-9 (1992)


Article DOI: 10.1021/jm00087a015
BindingDB Entry DOI: 10.7270/Q2KW5GPH
More data for this
Ligand-Target Pair