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BDBM50231514 CHEMBL4081641

SMILES: CCOC(=O)C1=C(C)NC(=O)N(CCC(=O)N\N=C\c2ccccc2)C1c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=KWHRWZXGZIRSQK-MFKUBSTINA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231514   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM50231514
PNG
(CHEMBL4081641)
Show SMILES CCOC(=O)C1=C(C)NC(=O)N(CCC(=O)N\N=C\c2ccccc2)C1c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1/C24H25N5O6/c1-3-35-23(31)21-16(2)26-24(32)28(22(21)18-10-7-11-19(14-18)29(33)34)13-12-20(30)27-25-15-17-8-5-4-6-9-17/h4-11,14-15,22H,3,12-13H2,1-2H3,(H,26,32)(H,27,30)/b25-15+
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.39E+3n/an/an/an/an/an/a



South Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of GFP-fused Cav3.2-alpha1 (unknown origin) expressed in human tsA-201 cells at holding potential of -110 mV by whole cell patch clamp met...


Bioorg Med Chem 25: 1926-1938 (2017)


Article DOI: 10.1016/j.bmc.2017.02.015
BindingDB Entry DOI: 10.7270/Q23F4RW9
More data for this
Ligand-Target Pair