BDBM50231640 CHEMBL285157::TCMDC-123457

SMILES C(N1CCC(=CC1)c1c[nH]c2ccccc12)c1ccccc1

InChI Key InChIKey=TYKXLUMYKFFSJE-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50231640   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  44nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]-ketanserin as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  354nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  923nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  933nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataIC50:  2.62E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataIC50:  2.63E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed