BDBM50231723 2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile::CHEMBL253349

SMILES CC1(C)CC(=O)c2cc(C#N)c(SCc3ccccc3)nc2C1

InChI Key InChIKey=WCUNNKNYJUBPJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231723   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231723(2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrah...)
Affinity DataIC50:  5.70E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231723(2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrah...)
Affinity DataIC50:  4.80E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed