BDBM50231791 CHEMBL4074296::US11725000, Compound 118
SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccc(=O)n(Cc2cccc(c2)C#N)c1
InChI Key InChIKey=RCZSVKJJLJDCQX-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50231791
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute Of Biological Sciences, Beijing
US Patent
National Institute Of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 1.05E+4nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute Of Biological Sciences, Beijing
US Patent
National Institute Of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 4.06E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair