BDBM50231807 CHEMBL4068001::US11725000, Compound 34

SMILES Cc1cc(nc(n1)S(C)(=O)=O)-c1cccs1

InChI Key InChIKey=OKDDBKXLKHCAME-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231807   

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50231807(CHEMBL4068001 | US11725000, Compound 34)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50231807(CHEMBL4068001 | US11725000, Compound 34)
Affinity DataEC50: <1.00E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50231807(CHEMBL4068001 | US11725000, Compound 34)
Affinity DataEC50:  817nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent