BDBM50231941 CHEMBL253103::N1-((2S,3R)-3-hydroxy-4-(isopropylamino)-1-phenylbutan-2-yl)-5-(N-methylmethan-3-ylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide

SMILES CC(C)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)S(C)(=O)=O

InChI Key InChIKey=TYLAFXLTQJYGOT-MXUAVAHLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231941   

TargetBeta-secretase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231941(CHEMBL253103 | N1-((2S,3R)-3-hydroxy-4-(isopropyla...)
Affinity DataKi:  425nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231941(CHEMBL253103 | N1-((2S,3R)-3-hydroxy-4-(isopropyla...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of memapsin 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed